Organs-on-a-Chip Technology

Plebani, Roberto et al. “Modeling pulmonary cystic fibrosis in a human lung airway-on-a-chip: Cystic fibrosis airway chip.” Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, S1569-1993(21)02106-8. 16 Nov. 2021, doi:10.1016/j.jcf.2021.10.004

Intestine Chip enables effective in vitro study of coronavirus infections of the human gut and testing of potential treatments. Lindsay Brownell, Wyss Institute for Biologically Inspired Engineering at Harvard University, Nov. 8, 2021.

Bein A, Kim S, Goyal G, et al. Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip. Front Pharmacol. 2021;12:718484. Published 2021 Oct 25. doi:10.3389/fphar.2021.718484.

Plebani, Roberto et al. “Modeling pulmonary cystic fibrosis in a human lung airway-on-a-chip: Cystic fibrosis airway chip.” Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, S1569-1993(21)02106-8. 16 Nov. 2021, doi:10.1016/j.jcf.2021.10.004

Human on a Chip: UBC’s Hedtrich Lab takes on Canada’s other Drug Crisis. From TREK: A Publication of Alumni UBC, June 15, 2021.

The Mini Lungs and Other Organoids Helping to Beat COVID, From Nature, News Feature, May 26, 2021.

On-chip perivascular niche supporting stemness of patient-derived glioma cells in a serum-free, flowable culture, May 5, 2021. From Royal Society of Chemistry.

Israelis Create Cancer Drug without Animal Tests, by Using Human-Simulating Chip, From The Times of Israel, https://www.timesofisrael.com/israelis-create-cancer-drug-using-human-simulating-chip-instead-of-animal-tests/?fbclid=IwAR3OfknmBRfuiYmlQrhKmNjq1RLgjSqj0fYZG6a8mQdejjhlFI08P8xWaM4

NIH Awards $25.5 Million to Use Tiny, Bioengineered Organ Models to Improve Clinical Trials’ Develoopment and Design, From National Center for Advancing Translational Sciences, Sept. 29, 2020.

Organ-on-a-chip-engineering: toward bridging-the-gap-between-lab-and-industry. From Biomicrofluidics
(July 14 2020)Download

How does COVID-19 invade our bodies so easily? U of T Engineering team uses ‘organ-on-a-chip’ model to find out. From U of T Engineering News (2020)

Device links up to 10 organ chips to form body-on-a-Chip, from WYSS Institute (2020)

Human organs-on-a-chip, WYSS Institute